GM2A antibody
Volume: 100 µg
Purification: Immunogen affinity purified
Form: liquid
Purity: 95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID:
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background: The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity(By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
Immunogen: GM2 ganglioside activator
Synonyms:
Observed MW: 22 kDa
Uniprot ID: P17900
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB, IP
Recommended dilution: WB: 1: 500-1: 2000; IP: 1: 200-1: 1000; IHC: 1: 20-1: 200
Gene ID: 2760
Research Area: Metabolism
Internal Reference:
FNab03517