Creatine Kinase MM-Specific antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: CKM, also named as CKMM and M-CK, is a member of the ATP: guanido phosphotransferase protein family. It is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. CKM reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissus,and as a heterodimer with a similar brain isozyme in heart. CK isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. CK MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, esp Immunogen: creatine kinase, muscle Synonyms: CKMM, Creatine Kinase MM, Creatine Kinase M-Specific, Creatine kinase M chain, Creatine kinase M type, creatine kinase, muscle, M CK Observed MW: 43 kDa Uniprot ID: P06732 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB, IHC, IF, IP Recommended dilution: WB: 1: 1000-1: 10000; IP: 1: 1000-1: 10000; IHC: 1: 20-1: 200; IF: 1: 10-1: 100 Gene ID: Research Area: Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology, Neuroscience