GNE Antibody

Size : 100 µL Clone Number: Aliases: 2310066H07Rik antibody; Bifunctional UDP N acetylglucosamine 2 epimerase/N acetylmannosamine kinase antibody; DMRV antibody; GLCNE_HUMAN antibody; Glucosamine (UDP N acetyl) 2 epimerase/N acetylmannosamine kinase antibody; GNE antibody; IBM2 antibody; ManAc kinase antibody; N acylmannosamine kinase antibody; N-acetylmannosamine kinase antibody; NM antibody; RP23-209M8.6 antibody; Uae1 antibody; UDP GlcNAc 2 epimerase antibody; UDP GlcNAc 2 epimerase/ManAc kinase antibody; UDP N acetylglucosamine 2 epimerase/N acetylmannosamine kinase antibody; UDP-GlcNAc-2-epimerase antibody; UDP-GlcNAc-2-epimerase/ManAc kinase antibody; Uridine diphosphate N acetylglucosamine 2 epimerase antibody; Uridine diphosphate-N-acetylglucosamine-2-epimerase antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9Y223 Immunogen: Synthesized peptide derived from C-terminal of Human GNE. Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IHC; WB: 1: 500-1: 3000, IHC: 1: 50-1: 100 Background: Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development By similarity. Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Lucka L., FEBS Lett. 454: 341-344(1999). Seppala R., Am. J. Hum. Genet. 64: 1563-1569(1999). Huizing M., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases. Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: GNE Research Areas: Cardiovascular;Developmental biology