GNL3L Antibody

Size : 50 µg Clone Number: Aliases: GNL3LGuanine nucleotide-binding protein-like 3-like protein antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9NVN8 Immunogen: Recombinant Human Guanine nucleotide-binding protein-like 3-like protein (1-582AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA Background: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: GNL3L Research Areas: Others