Cobra venom factor Antibody, FITC conjugated
Size : 50 µg
Clone Number:
Aliases: antibody; Cobra venom factor antibody; CVF antibody; CVFk antibody; Complement C3 homolog) [Cleaved into: Cobra venom factor alpha chain; Cobra venom factor gamma chain; Cobra venom factor beta chain] antibody
Product Type: Polyclonal Antibody
Immunogen Species: Naja kaouthia (Monocled cobra) (Naja siamensis)
UniProt ID: Q91132
Immunogen: Recombinant Naja kaouthia Cobra venom factor protein (733-984AA)
Host: Rabbit
Reactivity: Naja kaouthia
Tested Applications:
Background: Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity.
Clonality: Polyclonal
Isotype: IgG
Purification Method: 95%, Protein G purified
Conjugate: FITC
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:
Research Areas: Others