GNRHR Antibody

Size : 50 µL Clone Number: Aliases: GnRH receptor antibody; GnRH-R antibody; GNRHR antibody; GNRHR_HUMAN antibody; GNRHR1 antibody; Gonadotropin releasing hormone receptor antibody; gonadotropin-releasing hormone (type 1) receptor 1 antibody; Gonadotropin-releasing hormone receptor antibody; GRHR antibody; HH7 antibody; leutinizing-releasing hormone receptor antibody; lh-rh antibody; LHRHR antibody; LRHR antibody; luliberin receptor antibody; luteinizing hormone releasing hormone receptor antibody; type I GnRH receptor antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P30968 Immunogen: Synthetic peptide of Human GNRHR Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; ELISA: 1: 1000-1: 10000, WB: 1: 2000-1: 5000, IHC: 1: 150-1: 500 Background: This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: GNRHR Research Areas: Neuroscience